The stem cell road trip

Stem cell research is like a road trip. 

http://warwickcasculture.wordpress.com/2012/11/29/road-trip/

Just as roads and highways provide accessible routes for cars, publications and experimental technologies provide foundations for the progression of research hypotheses to meaningful scientific conclusions. For example, the production of induced pluripotent stem cells (iPSCs) from mice by Yamanaka in 2006 led to the development of iPSCs from human cells, paving the way for potential regenerative therapies and patient-specific 'disease-in-a-dish' modeling. 

Speed limits serve to warn and protect drivers, while research guidelines and regulations prevent false publications, ensuring sound, ethical research proposals and methodology. “The scientific method takes time and technology is not 100% fool proof” reminds Jen McCormick, Ph.D. bioethicist at the Mayo Clinic. “It’s important to understand the basic biology and how things work” regarding iPSCs and human embryonic stem cells and avoid “pushing direct to clinical use too quickly”. Policy dictates measures of safety and efficacy, which are paramount for successful clinical trials. As we venture further along the stem cell road, protocol must ensure smooth implementation in the medical setting. 

Ultimately, drivers determine the destinations and length of their trips as scientists do the direction and time course for their research projects. The more drivers in more vehicles, the more distance covered; the more researchers in diverse fields of science, the greater the potential to advance stem cell research on multiple fronts. “Scientists have an obligation not just educating, but also engaging in discussions” with the public, remarks Dr. McCormick. 

Buckle up and enjoy the ride!